Whitening and High-Dimensional Canonical Correlation Analysis R package whitening version 1.4.0 CRAN Task View: Omics (https://CRAN.R-project.org/view=Omics) Implements the whitening methods (ZCA, PCA, Cholesky, ZCA-cor, and PCA-cor) discussed in Kessy, Lewin, and Strimmer (2018) "Optimal whitening and decorrelation", <doi:10.1080/00031305.2016.1277159>, as well as the whitening approach to canonical correlation analysis allowing negative canonical correlations described in Jendoubi and Strimmer (2019) "A whitening approach to probabilistic canonical correlation analysis for omics data integration", <doi:10.1186/s12859-018-2572-9>. The package also offers functions to simulate random orthogonal matrices, compute (correlation) loadings and explained variation. It also contains four example data sets (extended UCI wine data, TCGA LUSC data, nutrimouse data, extended pitprops data). Software Depends: R (>= 3.5.0), corpcor (>= 1.6.10) Imports: stats Korbinian Strimmer <strimmerlab@gmail.com> Comprehensive R Archive Network (CRAN) Korbinian Strimmer, Takoua Jendoubi, Agnan Kessy, Alex Lewin GPL (>= 3) 2022-06-07 application/tgz https://CRAN.R-project.org/package=whitening doi:10.32614/CRAN.package.whitening