'VigiBase' Pharmacovigilance Database Toolbox R package vigicaen version 2.0.0 Perform the analysis of the World Health Organization (WHO) Pharmacovigilance database 'VigiBase' (Extract Case Level version), <https://who-umc.org/> e.g., load data, perform data management, disproportionality analysis, and descriptive statistics. Intended for pharmacovigilance routine use or studies. This package is NOT supported nor reflect the opinion of the WHO, or the Uppsala Monitoring Centre. Disproportionality methods are described by Norén et al (2013) <doi:10.1177/0962280211403604>. Software Depends: R (>= 4.1.0), Imports: arrow, cli, dplyr, data.table, ggplot2, glue, gridExtra, lifecycle, purrr, rlang, stringr, tidyr Suggests: here, knitr, rmarkdown, testthat (>= 3.0.0), tzdb, vdiffr Charles Dolladille <cdolladille@hotmail.com> Comprehensive R Archive Network (CRAN) Charles Dolladille [aut, cre] (ORCID: <https://orcid.org/0000-0003-0449-6261>), Basile Chrétien [aut] (ORCID: <https://orcid.org/0000-0002-7483-2489>), Universite de Caen Normandie [cph] (Caen, France), Unite de pharmaco-epidemiologie [cph] (Service de pharmacologie, Centre Hospitalier Universitaire de Caen, Caen, France) CeCILL-2.1 2026-06-24 application/tgz https://CRAN.R-project.org/package=vigicaen doi:10.32614/CRAN.package.vigicaen