Rapid Manipulation of the Variant Call Format (VCF) R package vcfppR version 0.8.3 The 'vcfpp.h' (<https://github.com/Zilong-Li/vcfpp>) provides an easy-to-use 'C++' 'API' of 'htslib', offering full functionality for manipulating Variant Call Format (VCF) files. The 'vcfppR' package serves as the R bindings of the 'vcfpp.h' library, enabling rapid processing of both compressed and uncompressed VCF files. Explore a range of powerful features for efficient VCF data manipulation. Software Depends: R (>= 3.6.0) Imports: Rcpp, methods, stats, utils LinkingTo: Rcpp Suggests: knitr, codetools, rmarkdown, testthat (>= 3.0.0) Zilong Li <zilong.dk@gmail.com> Comprehensive R Archive Network (CRAN) Zilong Li [aut, cre] (ORCID: <https://orcid.org/0000-0001-5859-2078>), Bonfield, James K and Marshall, John and Danecek, Petr and Li, Heng and Ohan, Valeriu and Whitwham, Andrew and Keane, Thomas and Davies, Robert M [cph] (Authors of included htslib library) MIT + file LICENSE (https://CRAN.R-project.org/package=vcfppR/LICENSE) 2026-03-31 application/tgz https://CRAN.R-project.org/package=vcfppR doi:10.32614/CRAN.package.vcfppR