PKPD, PBPK, and Systems Pharmacology Modeling Tools R package ubiquity version 2.1.0 CRAN Task View: Pharmacokinetics (https://CRAN.R-project.org/view=Pharmacokinetics) Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'. Software Depends: R (>= 4.2.0) Imports: cli, deSolve, dplyr (>= 1.0.0), digest, doParallel, flextable, foreach, ggplot2, knitr, MASS, onbrand (>= 1.0.2), optimx, PKNCA, pso, readxl, rmarkdown, rhandsontable, scales, stats, stringr, shiny, Suggests: babelmixr2, GA, GGally, gridGraphics, gridExtra, grid, officer, rxode2, webshot, ggrepel, rstudioapi, testthat John Harrold <john.m.harrold@gmail.com> Comprehensive R Archive Network (CRAN) John Harrold [aut, cre] (ORCID: <https://orcid.org/0000-0003-2052-4373>) BSD_2_clause + file LICENSE (https://CRAN.R-project.org/package=ubiquity/LICENSE) 2025-01-07 application/tgz https://CRAN.R-project.org/package=ubiquity doi:10.32614/CRAN.package.ubiquity