<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Sample Provenance Quality Resolver in Proteomics</dc:title>
  <dc:title>R package spqrp version 0.1.0</dc:title>
  <dc:description>Detect sample-provenance inconsistencies and potential mix-ups in mass-spectrometry-based
    plasma-proteome cohorts. Provides a clustering-based approach (build a
    nearest-neighbour graph in a dimensionality-reduced space and iteratively
    split large components by edge weight), a threshold-based approach
    (classify sample pairs as belonging or not-belonging from a pairwise
    distance cutoff), parameter optimization over distance metrics and
    cutoffs, and a pairwise random-forest classifier for protein importance
    ranking. This is a native R port of the author's Python package
    'spqrp' (&lt;https://github.com/fhradilak/spqrp&gt;), implementing methods from an associated manuscript currently in preparation.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.5.0)</dc:relation>
  <dc:relation>Imports: cli, dplyr (&gt;= 1.1.0), ggplot2 (&gt;= 3.5.0), igraph (&gt;= 2.0.0),
lgr, pROC, randomForest, ranger (&gt;= 0.16.0), rlang, solitude
(&gt;= 1.1.3), stats, tibble, tidyr (&gt;= 1.3.0), utils, withr</dc:relation>
  <dc:relation>Suggests: knitr, plotly (&gt;= 4.10.0), recipes, rmarkdown, smacof,
testthat (&gt;= 3.0.0), themis, uwot (&gt;= 0.2.0), vdiffr</dc:relation>
  <dc:creator>Franziska Hradilak &lt;Franziska.Hradilak@student.hpi.uni-potsdam.de&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Franziska Hradilak [aut, cre]</dc:contributor>
  <dc:rights>GPL-3</dc:rights>
  <dc:date>2026-06-17</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=spqrp</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.spqrp</dc:identifier>
</oai_dc:dc>
