<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Optimal Diagnostic Cutoff Selection under Scale Mixtures of
Skew-Normal Distributions</dc:title>
  <dc:title>R package smsncut version 0.1.0</dc:title>
  <dc:description>Implements a parametric decision-theoretic framework for optimal
    diagnostic cutoff selection under the family of scale mixtures of skew-normal
    (SMSN) distributions, including the skew-normal (SN) and skew-t (ST) models
    as special cases. The optimal cutoff is defined by minimising a weighted
    misclassification risk that incorporates disease prevalence and asymmetric
    costs, leading to a likelihood-ratio equation that generalises the Youden
    criterion. Under a monotone likelihood ratio condition, existence, uniqueness,
    and global optimality of the cutoff are established. Asymptotic normality and
    a closed-form plug-in variance estimator are provided via the implicit function
    theorem and the multivariate delta method. Tools for model fitting, cutoff
    estimation, confidence intervals, the local identifiability diagnostic, and
    Monte Carlo simulation are included. The methodology is described in
    de Paula, Mouriño, and Dias Domingues (2026)
    &lt;doi:10.48550/arXiv.2605.07829&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.1.0)</dc:relation>
  <dc:relation>Imports: sn (&gt;= 2.0.0), numDeriv (&gt;= 2016.8-1)</dc:relation>
  <dc:relation>Suggests: testthat (&gt;= 3.0.0), knitr, rmarkdown</dc:relation>
  <dc:creator>Renato de Paula &lt;rrpaula@ciencias.ulisboa.pt&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Renato de Paula [aut, cre] (ORCID:
    &lt;https://orcid.org/0000-0002-5835-5918&gt;),
  Helena Mouriño [aut],
  Tiago Dias Domingues [aut]</dc:contributor>
  <dc:rights>GPL-3</dc:rights>
  <dc:date>2026-05-19</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=smsncut</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.smsncut</dc:identifier>
</oai_dc:dc>
