<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Simulation of Pleiotropic, Linked and Epistatic Phenotypes</dc:title>
  <dc:title>R package simplePHENOTYPES version 1.3.0</dc:title>
  <dc:subject>CRAN Task View: Agriculture (https://CRAN.R-project.org/view=Agriculture)</dc:subject>
  <dc:description>The number of studies involving correlated traits and the availability of tools to handle this type of data has increased considerably in the last decade. With such a demand, we need tools for testing hypotheses related to single and multi-trait (correlated) phenotypes based on many genetic settings. Thus, we implemented various options for simulation of pleiotropy and Linkage Disequilibrium under additive, dominance and epistatic models. The simulation currently takes a marker data set as an input and then uses it for simulating multiple traits as described in Fernandes and Lipka (2020) &lt;doi:10.1186/s12859-020-03804-y&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.5.0)</dc:relation>
  <dc:relation>Imports: data.table, mvtnorm, stats, utils, SNPRelate, gdsfmt</dc:relation>
  <dc:relation>Suggests: knitr, rmarkdown</dc:relation>
  <dc:creator>Samuel Fernandes &lt;samuelf@illinois.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Samuel Fernandes [aut, cre] (ORCID:
    &lt;https://orcid.org/0000-0001-8269-535X&gt;),
  Alexander Lipka [aut] (ORCID: &lt;https://orcid.org/0000-0003-1571-8528&gt;)</dc:contributor>
  <dc:rights>MIT + file LICENSE (https://CRAN.R-project.org/package=simplePHENOTYPES/LICENSE)</dc:rights>
  <dc:date>2021-01-20</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=simplePHENOTYPES</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.simplePHENOTYPES</dc:identifier>
</oai_dc:dc>
