Segregation Analysis for Variant Interpretation R package segregatr version 0.5.0 An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) <doi:10.1086/378100>. This implementation supports custom penetrance values and liability classes, and allows visualisations and robustness analysis as presented in Ratajska et al. (2023) <doi:10.1002/mgg3.2107>. See also the online app 'shinyseg', <https://chrcarrizosa.shinyapps.io/shinyseg>, which offers interactive segregation analysis with many additional features (Carrizosa et al. (2024) <doi:10.1093/bioinformatics/btae201>). Software Depends: pedtools (>= 2.2.0), R (>= 4.1.0) Imports: pedprobr Suggests: testthat Magnus Dehli Vigeland <m.d.vigeland@medisin.uio.no> Comprehensive R Archive Network (CRAN) Magnus Dehli Vigeland [aut, cre] (ORCID: <https://orcid.org/0000-0002-9134-4962>), Christian Carrizosa [aut] (ORCID: <https://orcid.org/0000-0002-3919-0011>) GPL-3 2025-08-26 application/tgz https://CRAN.R-project.org/package=segregatr doi:10.32614/CRAN.package.segregatr en-GB