Average Bioequivalence with Expanding Limits (ABEL) R package replicateBE version 1.1.3 CRAN Task View: ClinicalTrials (https://CRAN.R-project.org/view=ClinicalTrials) CRAN Task View: Pharmacokinetics (https://CRAN.R-project.org/view=Pharmacokinetics) Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' / 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well. Software Depends: R (>= 3.5.0) Imports: readxl (>= 1.0.0), PowerTOST (>= 1.5.3), lmerTest, nlme, pbkrtest, graphics, grDevices Suggests: knitr, rmarkdown, testthat, devtools Helmut Schütz <helmut.schuetz@bebac.at> Comprehensive R Archive Network (CRAN) Helmut Schütz [aut, cre] (ORCID: <https://orcid.org/0000-0002-1167-7880>), Michael Tomashevskiy [ctb], Detlew Labes [ctb] (ORCID: <https://orcid.org/0000-0003-2169-426X>) GPL (>= 3) 2022-05-02 application/tgz https://CRAN.R-project.org/package=replicateBE doi:10.32614/CRAN.package.replicateBE