Multiple-Instance Logistic Regression with LASSO Penalty R package milr version 0.4.1 The multiple instance data set consists of many independent subjects (called bags) and each subject is composed of several components (called instances). The outcomes of such data set are binary or categorical responses, and, we can only observe the subject-level outcomes. For example, in manufacturing processes, a subject is labeled as "defective" if at least one of its own components is defective, and otherwise, is labeled as "non-defective". The 'milr' package focuses on the predictive model for the multiple instance data set with binary outcomes and performs the maximum likelihood estimation with the Expectation-Maximization algorithm under the framework of logistic regression. Moreover, the LASSO penalty is attached to the likelihood function for simultaneous parameter estimation and variable selection. Software Depends: R (>= 3.2.3) Imports: utils, pipeR (>= 0.5), numDeriv, glmnet, Rcpp (>= 0.12.0), RcppParallel LinkingTo: Rcpp, RcppArmadillo, RcppParallel Suggests: testthat, knitr, Hmisc, rmarkdown, data.table, ggplot2, plyr Ping-Yang Chen <pychen.ping@gmail.com> Comprehensive R Archive Network (CRAN) Ping-Yang Chen [aut, cre], ChingChuan Chen [aut], Chun-Hao Yang [aut], Sheng-Mao Chang [aut] MIT + file LICENSE (https://CRAN.R-project.org/package=milr/LICENSE) 2025-09-19 application/tgz https://CRAN.R-project.org/package=milr doi:10.32614/CRAN.package.milr