Causal Mediation Analysis R package mediation version 4.5.1 CRAN Task View: CausalInference (https://CRAN.R-project.org/view=CausalInference) CRAN Task View: Epidemiology (https://CRAN.R-project.org/view=Epidemiology) CRAN Task View: Psychometrics (https://CRAN.R-project.org/view=Psychometrics) We implement parametric and non parametric mediation analysis. This package performs the methods and suggestions in Imai, Keele and Yamamoto (2010) <DOI:10.1214/10-STS321>, Imai, Keele and Tingley (2010) <DOI:10.1037/a0020761>, Imai, Tingley and Yamamoto (2013) <DOI:10.1111/j.1467-985X.2012.01032.x>, and Imai and Yamamoto (2013) <DOI:10.1093/pan/mps040>. In addition to the estimation of causal mediation effects, the software also allows researchers to conduct sensitivity analysis for certain parametric models. Software Depends: R (>= 2.15.1), MASS, Matrix, mvtnorm, sandwich Imports: lpSolve, Hmisc, lme4 (>= 1.0), stats, graphics, grDevices, utils, boot Suggests: mgcv, quantreg, VGAM, SuppDists, survival, parallel, testthat, speedglm Teppei Yamamoto <tyamam@waseda.jp> Comprehensive R Archive Network (CRAN) Dustin Tingley [aut], Teppei Yamamoto [aut, cre], Kentaro Hirose [aut], Luke Keele [aut], Kosuke Imai [aut], Minh Trinh [aut], Weihuang Wong [aut] GPL (>= 2) 2025-06-07 application/tgz https://CRAN.R-project.org/package=mediation doi:10.32614/CRAN.package.mediation