In Vitro Toxicokinetic Data Processing and Analysis Pipeline R package invitroTKstats version 0.0.14 A set of tools for processing and analyzing in vitro toxicokinetic measurements in a standardized and reproducible pipeline. The package was developed to perform frequentist and Bayesian estimation on a variety of in vitro toxicokinetic measurements including -- but not limited to -- chemical fraction unbound in the presence of plasma (f_up), intrinsic hepatic clearance (Clint, uL/min/million hepatocytes), and membrane permeability for oral absorption (Caco2). The methods provided by the package were described in Wambaugh et al. (2019) <doi:10.1093/toxsci/kfz205>. Software Depends: R (>= 3.5.0) Imports: runjags, parallel, readxl, coda, ggplot2, scales, stats4, Rdpack, methods, stats, utils, dplyr, rlang Suggests: knitr, R.rsp, tidyverse, gridExtra, gridtext, flextable, rmarkdown, magrittr, stringr Caroline Ring <ring.caroline@epa.gov> Comprehensive R Archive Network (CRAN) John Wambaugh [aut] (ORCID: <https://orcid.org/0000-0002-4024-534X>), Caroline Ring [cre] (ORCID: <https://orcid.org/0000-0002-0463-1251>), Sarah E. Davidson-Fritz [aut] (ORCID: <https://orcid.org/0000-0002-2891-9380>), Lindsay Knupp [ctb], Barbara A. Wetmore [ctb] (ORCID: <https://orcid.org/0000-0002-6878-5348>), Zhao Zhihui [ctb], Chantel Nicolas [ctb] (ORCID: <https://orcid.org/0000-0003-2061-5830>), Anna Kreutz [ctb] (ORCID: <https://orcid.org/0000-0002-7787-0683>), U.S. Federal Government [cph] (Copyright holder of this package) MIT + file LICENSE (https://CRAN.R-project.org/package=invitroTKstats/LICENSE) 2026-01-26 application/tgz https://CRAN.R-project.org/package=invitroTKstats doi:10.32614/CRAN.package.invitroTKstats