A Comprehensive Toolkit for Clinical HLA Informatics R package immunogenetr version 1.4.0 A comprehensive toolkit for clinical Human Leukocyte Antigen (HLA) informatics, built on 'tidyverse' <https://tidyverse.tidyverse.org/> principles and making use of Genotype List String (GL String, Mack et al. (2023) <doi:10.1111/tan.15126>) for storing and computing HLA genotype data. Specific functionalities include: coercion of HLA data in tabular format to and from GL String; calculation of matching and mismatching in all directions, with multiple output formats; automatic formatting of HLA data for searching within a GL String; truncation of molecular HLA data to a specific number of fields; and reading HLA genotypes in HML files and extracting the GL String. This library is intended for research use. Any application making use of this package in a clinical setting will need to be independently validated according to local regulations. Software Depends: R (>= 4.1.0) Imports: cli (>= 3.0.0), dplyr (>= 1.1.1), purrr (>= 1.0.2), rlang (>= 1.1.2), stringi (>= 1.7.0), stringr (>= 1.5.0), tibble (>= 3.1.3), tidyr (>= 1.3.0), tidyselect (>= 1.2.0), xml2 (>= 1.3.6) Suggests: knitr, rmarkdown, testthat (>= 3.0.0) Nicholas Brown <nicholas.brown@pennmedicine.upenn.edu> Comprehensive R Archive Network (CRAN) Nicholas Brown [cre, aut] (ORCID: <https://orcid.org/0000-0002-0046-2315>), Busra Coskun [aut] (ORCID: <https://orcid.org/0009-0008-6828-3453>) GPL (>= 3) 2026-07-06 application/tgz https://CRAN.R-project.org/package=immunogenetr doi:10.32614/CRAN.package.immunogenetr en-US