<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>B Cell Receptor Phylogenetics Toolkit</dc:title>
  <dc:title>R package dowser version 2.4.1</dc:title>
  <dc:description>Provides a set of functions for inferring, visualizing, and analyzing B cell phylogenetic trees.
    Provides methods to 1) reconstruct unmutated ancestral sequences,
    2) build B cell phylogenetic trees using multiple methods,
    3) visualize trees with metadata at the tips,
    4) reconstruct intermediate sequences,
    5) detect biased ancestor-descendant relationships among metadata types
    Workflow examples available at documentation site (see URL).
    Citations:
    Hoehn et al (2022) &lt;doi:10.1371/journal.pcbi.1009885&gt;,
    Hoehn et al (2021) &lt;doi:10.1101/2021.01.06.425648&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.4), ggplot2 (&gt;= 3.4.0)</dc:relation>
  <dc:relation>Imports: airr, alakazam (&gt;= 1.1.0), ape (&gt;= 5.6), dplyr (&gt;= 1.0),
ggtree, graphics, gridExtra, markdown, methods, phangorn (&gt;=
2.7.1), phylotate, RColorBrewer, rlang, shazam (&gt;= 1.1.1),
stats, stringr, tidyselect, tidyr, utils, pwalign, treeio</dc:relation>
  <dc:relation>Suggests: knitr, rmarkdown, testthat, BiocManager</dc:relation>
  <dc:creator>Kenneth Hoehn &lt;kenneth.b.hoehn@dartmouth.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Kenneth Hoehn [aut, cre],
  Cole Jensen [aut],
  Jessie Fielding [aut],
  Hunter Melton [aut],
  Susanna Marquez [ctb],
  Jason Vander Heiden [ctb],
  Steven Kleinstein [aut, cph]</dc:contributor>
  <dc:rights>AGPL-3</dc:rights>
  <dc:date>2026-03-26</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=dowser</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.dowser</dc:identifier>
</oai_dc:dc>
