<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Blocking and Randomization for Experimental Design</dc:title>
  <dc:title>R package designit version 0.5.0</dc:title>
  <dc:description>
    Intelligently assign samples to batches in order to reduce batch effects.
    Batch effects can have a significant impact on data analysis, especially
    when the assignment of samples to batches coincides with the contrast
    groups being studied. By defining a batch container and a scoring function
    that reflects the contrasts, this package allows users to assign samples in
    a way that minimizes the potential impact of batch effects on the
    comparison of interest. Among other functionality, we provide an
    implementation for OSAT score by Yan et al. (2012,
    &lt;doi:10.1186/1471-2164-13-689&gt;).</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.1.0)</dc:relation>
  <dc:relation>Imports: rlang (&gt;= 0.4.0), dplyr (&gt;= 1.0.0), purrr, ggplot2, scales,
tibble, tidyr, assertthat, stringr, R6, data.table, stats</dc:relation>
  <dc:relation>Suggests: testthat, roxygen2, pkgdown, knitr, markdown, rmarkdown, gt,
bench, OSAT, tidyverse, printr, devtools (&gt;= 2.0.0), ggpattern,
cowplot, bestNormalize, here</dc:relation>
  <dc:creator>Iakov I. Davydov &lt;iakov.davydov@roche.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Iakov I. Davydov [aut, cre, cph] (ORCID:
    &lt;https://orcid.org/0000-0003-3510-3926&gt;),
  Juliane Siebourg-Polster [aut, cph] (ORCID:
    &lt;https://orcid.org/0000-0002-1759-3223&gt;),
  Guido Steiner [aut, cph],
  Konrad Rudolph [ctb] (ORCID: &lt;https://orcid.org/0000-0002-9866-7051&gt;),
  Jitao David Zhang [aut, cph] (ORCID:
    &lt;https://orcid.org/0000-0002-3085-0909&gt;),
  Balazs Banfai [aut, cph] (ORCID:
    &lt;https://orcid.org/0000-0003-0422-7977&gt;),
  F. Hoffman-La Roche [cph, fnd]</dc:contributor>
  <dc:rights>MIT + file LICENSE (https://CRAN.R-project.org/package=designit/LICENSE)</dc:rights>
  <dc:date>2024-03-21</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=designit</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.designit</dc:identifier>
</oai_dc:dc>
