Provides tools to safely and efficiently organize and execute 
    Monte Carlo simulation experiments in R.
    The package controls the structure and back-end of Monte Carlo simulation experiments
    by utilizing a generate-analyse-summarise workflow. The workflow safeguards against 
    common simulation coding issues, such as automatically re-simulating non-convergent results, 
    prevents inadvertently overwriting simulation files, catches error and warning messages
    during execution, implicitly supports parallel processing with high-quality random number 
    generation, and provides tools for managing high-performance computing (HPC) array jobs
    submitted to schedulers such as SLURM. For a pedagogical introduction to the package see
    Sigal and Chalmers (2016) <doi:10.1080/10691898.2016.1246953>. For a more in-depth overview of 
    the package and its design philosophy see Chalmers and Adkins (2020) <doi:10.20982/tqmp.16.4.p248>.

Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) <doi:10.1002/sim.7689> for details.

Assessment of the distributions of baseline continuous and categorical 
    variables in randomised trials. This method is based on the Carlisle-Stouffer 
    method with Monte Carlo simulations. It calculates p-values for each trial 
    baseline variable, as well as combined p-values for each trial - these p-values 
    measure how compatible are distributions of trials baseline variables with 
    random sampling. This package also allows for graphically plotting the 
    cumulative frequencies of computed p-values.
    Please note that code was partly adapted from Carlisle JB, Loadsman JA. 
    (2017) <doi:10.1111/anae.13650>.