Several procedures for the hierarchical kernel extreme value process of Reich and Shaby (2012) <DOI:10.1214/12-AOAS591>, including simulation, estimation and spatial extrapolation. The spatial latent variable model <DOI:10.1214/11-STS376> is also included.

Functions, Shiny apps and data for the book "Introduction to Statistics" by
   Wolfgang Karl Härdle, Sigbert Klinke, and Bernd Rönz (2015) <doi:10.1007/978-3-319-17704-5>.

A streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting 'HLAMatchMaker' <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.

A toolkit for the analysis and management of data for genes in the so-called "Human Leukocyte Antigen" (HLA) region. Functions extract reference data from the Anthony Nolan HLA Informatics Group/ImmunoGeneTics HLA 'GitHub' repository (ANHIG/IMGTHLA) <https://github.com/ANHIG/IMGTHLA>, validate Genotype List (GL) Strings, convert between UNIFORMAT and GL String Code (GLSC) formats, translate HLA alleles and GLSCs across ImmunoPolymorphism Database (IPD) IMGT/HLA Database release versions, identify differences between pairs of alleles at a locus, generate customized, multi-position sequence alignments, trim and convert allele-names across nomenclature epochs, and extend existing data-analysis methods. Tran et al., (2025) <doi:10.1111/iji.70013>.

Calculates Herd Lying Concordance (HLC) metrics from individual animal lying-behaviour data. HLC is a continuous framework for quantifying group-level behavioural cohesion from between-animal dispersion within observation intervals. The package implements standard deviation, mean absolute deviation, interquartile range, and entropy formulations, lying-weighted extensions, threshold-based synchrony comparisons, temporal summaries, and descriptive method-ranking tools. The HLC formulations are introduced in this package; related approaches to cattle behavioural synchrony include Raussi et al. (2011) <doi:10.1017/S1751731110001928>, Kok et al. (2023) <doi:10.1016/j.applanim.2023.105906>, and the activity metric framework of van Dixhoorn et al. (2024) <doi:10.24072/pcjournal.489>.