The graphical approach is proposed as a general framework for clinical trial designs involving multiple hypotheses, where decisions are made only based on the observed marginal p-values. A reverse graphical approach starts from a set of singleton graphs, and gradually add vertices into graphs until rejection of a set of hypotheses is made. See Gou, J. (2020). Reverse graphical approaches for multiple test procedures. Technical Report.

The visualization tool offers a nuanced understanding of regression dynamics, going beyond traditional per-unit interpretation of continuous variables versus categorical ones. It highlights the impact of unit changes as well as larger shifts like interquartile changes, acknowledging the distribution of empirical data. Furthermore, it generates visualizations depicting alterations in Odds Ratios for predictors across minimum, first quartile, median, third quartile, and maximum values, aiding in comprehending predictor-outcome interplay within empirical data distributions, particularly in logistic regression frameworks.

An R6 class "Replacer" provided by the package simplifies working with
    regex patterns containing named groups. It allows easy retrieval of matched portions
    and targeted replacements by group name, improving both code clarity and maintainability.

Functions to fit Gaussian linear model by maximising the
        residual log likelihood where the covariance structure can be
        written as a linear combination of known matrices.  Can be used
        for multivariate models and random effects models.  Easy
        straight forward manner to specify random effects models,
        including random interactions. Code now optimised to use
        Sherman Morrison Woodbury identities for matrix inversion in
        random effects models. We've added the ability to fit models
        using any kernel as well as a function to return the mean and
        covariance of random effects conditional on the data (best
        linear unbiased predictors, BLUPs).
        Clifford and McCullagh (2006)
        <https://www.r-project.org/doc/Rnews/Rnews_2006-2.pdf>.