Translating messages in R packages is managed using the po
    top-level directory and the 'gettext' program. This package provides
    some helper functions for building this support in R packages, e.g.
    common validation & I/O tasks.

Do Markov chain Monte Carlo (MCMC) simulation of Potts models
   (Potts, 1952, <doi:10.1017/S0305004100027419>),
   which are the multi-color generalization of Ising models
   (so, as as special case, also simulates Ising models).
   Use the Swendsen-Wang algorithm (Swendsen and Wang, 1987,
   <doi:10.1103/PhysRevLett.58.86>) so MCMC is fast.
   Do maximum composite likelihood estimation of parameters
   (Besag, 1975, <doi:10.2307/2987782>,
   Lindsay, 1988, <doi:10.1090/conm/080>).

There are three sets of functions. The first produces
             basic properties of a graph and generates samples from
             multinomial distributions to facilitate the simulation
	     functions (they maybe used for other purposes as well).
	     The second provides various simulation functions for a
	     Potts model in Potts, R. B. (1952)
	     <doi:10.1017/S0305004100027419>.
	     The third currently includes only one function which
	     computes the normalizing constant of a Potts model
	     based on simulation results.

Computes the D', Wn, and conditional asymmetric linkage disequilibrium (ALD) measures for pairs of genetic loci. Performs these linkage disequilibrium (LD) calculations on phased genotype data recorded using Genotype List (GL) String or columnar formats. Alternatively, generates expectation-maximization (EM) estimated haplotypes from phased data, or performs LD calculations on EM estimated haplotypes. Performs sign tests comparing LD values for phased and unphased datasets, and generates heat-maps for each LD measure. Described by Osoegawa et al. (2019a) <doi:10.1016/j.humimm.2019.01.010>, and Osoegawa et. al. (2019b) <doi:10.1016/j.humimm.2019.05.018>.

An implementation of the Partition Of variation (POV) method as
    developed by Dr. Thomas A Little <https://thomasalittleconsulting.com> in
    1993 for the analysis of semiconductor data for hard drive manufacturing.
    POV is based on sequential sum of squares and is an exact method that
    explains all observed variation. It quantitates both the between and within
    factor variation effects and can quantitate the influence of both continuous
    and categorical factors.