A collection of R functions for use with Stock Synthesis, a
    fisheries stock assessment modeling platform written in ADMB by Dr. Richard
    D. Methot at the NOAA Northwest Fisheries Science Center. The functions
    include tools for summarizing and plotting results, manipulating files,
    visualizing model parameterizations, and various other common stock
    assessment tasks.
    This version of '{r4ss}' is compatible with Stock Synthesis versions
    3.24 through 3.30 (specifically version 3.30.19.01, from April
    2022).

The 'r4sub' package is a meta-package that installs and loads
    core packages of the R4SUB (R for Regulatory Submission) clinical
    submission readiness ecosystem. Loading 'r4sub' attaches 'r4subcore',
    'r4subtrace', 'r4subscore', 'r4subrisk', 'r4subdata', and
    'r4subprofile'.

Foundational package in the R4SUB (R for Regulatory Submission)
    ecosystem. Defines the core evidence table schema, parsers, indicator
    abstractions, and scoring primitives needed to quantify clinical submission
    readiness. Provides a standardized contract for ingesting heterogeneous
    sources (validation outputs, metadata, traceability) into a single
    evidence framework.

Provides realistic synthetic example datasets for the R4SUB
    (R for Regulatory Submission) ecosystem. Includes a pharma study evidence
    table, ADaM (Analysis Data Model) and SDTM (Study Data Tabulation Model)
    metadata following CDISC (Clinical Data Interchange Standards Consortium)
    conventions (<https://www.cdisc.org>), traceability mappings, a risk
    register based on ICH (International Council for Harmonisation) Q9
    quality risk management principles
    (<https://www.ich.org/page/quality-guidelines>), and regulatory indicator
    definitions. Designed for demos, vignettes, and package testing.

Defines submission profiles per regulatory authority with
    authority-specific pillar weights, decision thresholds, indicator
    requirements, and risk configuration. Supports the U.S. Food and Drug
    Administration (FDA), European Medicines Agency (EMA), Pharmaceuticals and
    Medical Devices Agency (PMDA), Health Canada, Therapeutic Goods
    Administration (TGA), and Medicines and Healthcare products Regulatory
    Agency (MHRA). Integrates with 'r4subscore' and 'r4subrisk' configuration
    systems.