Deconvolution of bulk RNA-Sequencing data into proportions of cells based on a reference single-cell RNA-Sequencing dataset using high-dimensional geometric methodology <doi:10.64898/2026.01.24.701240>.

Data from statistical agencies and other institutions often
    need to be protected before they can be published. This package 
    can be used to perturb statistical tables in a consistent way. The
    main idea is to add - at the micro data level - a record key for each
    unit. Based on these keys, for any cell in a statistical table a
    cell key is computed as a function on the record keys contributing to
    a specific cell. Values that are added to the cell in order to perturb
    it are derived from a lookup-table that maps values of cell keys to 
    specific perturbation values. The theoretical basis for the methods 
    implemented can be found in Thompson, Broadfoot and Elazar 
    (2013) <https://unece.org/fileadmin/DAM/stats/documents/ece/ces/ge.46/2013/Topic_1_ABS.pdf>
    which was extended and enhanced by Giessing and Tent 
    (2019) <https://unece.org/fileadmin/DAM/stats/documents/ece/ces/ge.46/2019/mtg1/SDC2019_S2_Germany_Giessing_Tent_AD.pdf>.

Provides functions to generate frequency tables and apply cell key
    perturbation to protect against statistical disclosure in tabular outputs.
    The implemented methods are described in "Cell Key Perturbation User Guide"
    <https://github.com/ONSdigital/cell-key-perturbation-R/blob/main/documentation/SML_UserDoc_CKP_R.md>.
    Developed at the UK Office for National Statistics.

Finds the most likely originating tissue(s) and developmental stage(s) of tissue-specific RNA sequencing data. The package identifies both pure transcriptomes and mixtures of transcriptomes. The most likely identity is found through comparisons of the sequencing data with high-throughput in situ hybridisation patterns. Typical uses are the identification of cancer cell origins, validation of cell culture strain identities, validation of single-cell transcriptomes, and validation of identity and purity of flow-sorting and dissection sequencing products.