Write blog posts and web pages in R Markdown. This package
    supports the static site generator 'Hugo' (<https://gohugo.io>) best,
    and it also supports 'Jekyll' (<https://jekyllrb.com>) and 'Hexo'
    (<https://hexo.io>).

Provides methods for estimating the area under the concentration
    versus time curve (AUC) and its standard error in the presence of Below the
    Limit of Quantification (BLOQ) observations. Two approaches are implemented:
    direct estimation using censored maximum likelihood, and a two-step approach
    that first imputes BLOQ values using various methods and then computes the
    AUC using the imputed data. Technical details are described in Barnett et al.
    (2020), "Methods for Non-Compartmental Pharmacokinetic Analysis With
    Observations Below the Limit of Quantification," Statistics in
    Biopharmaceutical Research. <doi:10.1080/19466315.2019.1701546>.

Tools designed to make it easier for beginner and intermediate users to build and validate 
    binary logistic regression models. Includes bivariate analysis, comprehensive regression output, 
    model fit statistics, variable selection procedures, model validation techniques and a 'shiny' 
    app for interactive model building.

Arrays of structured data types can require large volumes of disk
    space to store. 'Blosc' is a library that provides a fast and efficient way
    to compress such data. It is often applied in storage of n-dimensional
    arrays, such as in the case of the geo-spatial 'zarr' file format. This
    package can be used to compress and decompress data using 'Blosc'.

Finds the best block diagonal matrix approximation of a symmetric matrix. This can be exploited for divisive hierarchical clustering using singular vectors, named HC-SVD. The method is described in Bauer (202Xa) <doi:10.48550/arXiv.2308.06820>.

Provides the estimation algorithm to perform the demand estimation described in Berry, Levinsohn and Pakes (1995) <DOI:10.2307/2171802> . The routine uses analytic gradients and offers a large number of implemented integration methods and optimization routines.