The modified Adult Treatment Panel -III guidelines (ATP-III) proposed by American Heart Association (AHA) and National Heart, Lung and Blood Institute (NHLBI) are used widely for the clinical diagnosis of Metabolic Syndrome. The AHA-NHLBI criteria advise using parameters such as waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting plasma glucose (FPG), triglycerides (TG) and high-density lipoprotein cholesterol (HDLC) for diagnosis of metabolic syndrome. Each parameter has to be interpreted based on the proposed cut-offs, making the diagnosis slightly complex and error-prone. This package is developed by incorporating the modified ATP-III guidelines, and it will aid in the easy and quick diagnosis of metabolic syndrome in busy healthcare settings and also for research purposes. The modified ATP-III-AHA-NHLBI criteria for the diagnosis is described by Grundy et al ., (2005) <doi:10.1161/CIRCULATIONAHA.105.169404>.

A set of functions to investigate raw data from (metabol)omics experiments intended to be used on a raw data matrix, i.e. following peak picking and signal deconvolution. Functions can be used to normalize data, detect biomarkers and perform sample classification. A detailed description of best practice usage may be found in the publication <doi:10.1007/978-1-4939-7819-9_20>.

Provides a framework to perform soft clustering using 
        simplex-structured matrix factorisation (SSMF). The package contains a set of functions
        for determining the optimal number of prototypes, the optimal algorithmic
        parameters, the estimation confidence intervals and the diversity of clusters.
        Abdolali, Maryam & Gillis, Nicolas (2020) <doi:10.1137/20M1354982>.

Data sets and code supporting the second edition of "Meta-Analysis with R"; first edition: Schwarzer, Carpenter, and Rücker (2015) <DOI:10.1007/978-3-319-21416-0>.

Takes QC signal for each day and normalize metabolomic
    data that has been acquired in a certain period of time. At least
    three QC per day are required.