Compare variables of interest between (potentially large
    numbers of) spatial interactions and meta-variables. Spatial variables
    are summarized using K, or other, functions, and projected for use in
    a modified random forest model. The model allows comparison of
    functional and non-functional variables to each other and to noise,
    giving statistical significance to the results. Included are
    preparation, modeling, and interpreting tools along with example
    datasets, as described in VanderDoes et al., (2023)
    <doi:10.1101/2023.07.18.549619>.

Allows generating heatmap-like visualisations for data 
  frames. Funky heatmaps can be fine-tuned by providing annotations of the 
  columns and rows, which allows assigning multiple palettes or geometries
  or grouping rows and columns together in categories.
  Saelens et al. (2019) <doi:10.1038/s41587-019-0071-9>.

The funLBM algorithm allows to simultaneously cluster the rows and the columns of a data matrix where each entry of the matrix is a function or a time series.

Fits a functional mediation model with a scalar distal outcome. The method is described in detail by Coffman, Dziak, Litson, Chakraborti, Piper & Li (2021) <arXiv:2112.03960>. The model is similar to that of Lindquist (2012) <doi:10.1080/01621459.2012.695640> although allowing a binary outcome as an alternative to a numerical outcome.  The current version is a minor bug fix in the vignette. The development of this package was part of a research project supported by National Institutes of Health grants P50 DA039838 from the National Institute of Drug Abuse and 1R01 CA229542-01 from the National Cancer Institute and the NIH Office of Behavioral and Social Science Research. Content is solely the responsibility of the authors and does not necessarily represent the official views of the funding institutions mentioned above. This software is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details.