Provides robust parameter tuning and model training for predictive models applied across data sources where the data distribution varies slightly from source to source. This package implements three primary tuning methods: cross-validation-based internal tuning, external tuning, and the 'RobustTuneC' method. External tuning includes a conservative option where parameters are tuned internally on the training data and validating on an external dataset, providing a slightly pessimistic estimate. It supports Lasso, Ridge, Random Forest, Boosting, and Support Vector Machine classifiers. Currently, only binary classification is supported. The response variable must be the first column of the dataset and a factor with exactly two levels. The tuning methods are based on the paper by Nicole Ellenbach, Anne-Laure Boulesteix, Bernd Bischl, Kristian Unger, and Roman Hornung (2021) "Improved Outcome Prediction Across Data Sources Through Robust Parameter Tuning" <doi:10.1007/s00357-020-09368-z>.

Implements two-sample tests for paired data with missing values (Fong, Huang, Lemos and McElrath 2018, Biostatics, <doi:10.1093/biostatistics/kxx039>) and modified Wilcoxon-Mann-Whitney two sample location test, also known as the Fligner-Policello test.

Methods for aggregating ranked lists, especially lists of
    genes. It implements the Robust Rank Aggregation Kolde et al (2012)
    <doi:10.1093/bioinformatics/btr709> and some other simple algorithms 
    for the task. RRA method uses a probabilistic model for aggregation that 
    is robust to noise and also facilitates the calculation of significance
    probabilities for all the elements in the final ranking.

A collection of functions to compute the Rao-Stirling diversity index
	(Porter and Rafols, 2009) <DOI:10.1007/s11192-008-2197-2> and its extension to
	acknowledge missing data (i.e.,	uncategorized references) by calculating its
	interval of uncertainty using	mathematical optimization as proposed in Calatrava
	et al. (2016) <DOI:10.1007/s11192-016-1842-4>.
	The Rao-Stirling diversity index is a well-established bibliometric indicator
	to measure the interdisciplinarity of scientific publications. Apart from the
	obligatory dataset of publications with their respective references and	a
	taxonomy of disciplines that categorizes references as well as a measure of
	similarity between the disciplines, the Rao-Stirling diversity index requires
	a complete categorization of all references of a publication into disciplines.
	Thus, it fails for a incomplete categorization; in this case, the robust
	extension has to be used, which encodes the uncertainty caused by missing
	bibliographic data as an uncertainty interval.
	Classification / ACM - 2012: Information systems ~ Similarity measures,
	Theory of computation ~ Quadratic	programming, Applied computing ~ Digital
	libraries and archives.