A subgroup identification method for precision medicine based on 
    quantitative objectives. This method can handle continuous, binary and 
    survival endpoint for both prognostic and predictive case. For the 
    predictive case, the method aims at identifying a subgroup for which 
    treatment is better than control by at least a pre-specified or 
    auto-selected constant. For the prognostic case, the method aims at 
    identifying a subgroup that is at least better than a 
    pre-specified/auto-selected constant. The derived signature is a linear 
    combination of predictors, and the selected subgroup are subjects with 
    the signature > 0. The false discover rate when no true subgroup exists
    is controlled at a user-specified level.

Algorithms for accelerating the convergence of slow, monotone 
    sequences from smooth, contraction mappings such as the EM algorithm. 
    It can be used to accelerate any smooth, linearly convergent scheme. 
    A tutorial-style introduction is available in vignette("SQUAREM"). 
    See also: Varadhan & Roland (2008) <doi:10.18637/jss.v092.i07>.

Functions for color-based visualization of multivariate data, i.e. colorgrams or heatmaps.  Lower-level functions  map numeric values to colors, display a matrix as an array of colors, and draw color keys.  Higher-level plotting functions generate a bivariate histogram, a dendrogram aligned with a color-coded matrix, a triangular distance matrix, and more.

An implementation of statistical tools for the analysis 
    of rotation-valued time series and functional data. It relies on 
    pre-existing quaternion data structure provided by the 'Eigen' 'C++' 
    library.

Data processing and visualizations for rodent vocalizations exported from
    'DeepSqueak'. These functions are compatible with the 'SqueakR' Shiny Dashboard,
    which can be used to visualize experimental results and analyses.

A simulation-based tool made to help researchers to become familiar with
    multilevel variations, and to build up sampling designs for their study. 
    This tool has two main objectives: First, it provides an educational tool useful for students, 
    teachers and researchers who want to learn to use mixed-effects models. 
    Users can experience how the mixed-effects model framework can be used to understand 
    distinct biological phenomena by interactively exploring simulated multilevel data. 
    Second, it offers research opportunities to those who are already familiar with 
    mixed-effects models, as it enables the generation of data sets that users may download 
    and use for a range of simulation-based statistical analyses such as power 
    and sensitivity analysis of multilevel and multivariate data [Allegue, H., Araya-Ajoy, Y.G., Dingemanse, 
    N.J., Dochtermann N.A., Garamszegi, L.Z., Nakagawa, S., Reale, D., Schielzeth, H. and Westneat, D.F. (2016) 
    <doi: 10.1111/2041-210X.12659>].