<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Simulation and Analysis Tools for Clinical Dose Response
Modeling</dc:title>
  <dc:title>R package clinDR version 2.5.2</dc:title>
  <dc:subject>CRAN Task View: Pharmacokinetics (https://CRAN.R-project.org/view=Pharmacokinetics)</dc:subject>
  <dc:description>Bayesian and ML Emax model fitting, graphics and simulation for clinical dose
    response.  The summary data from the dose response meta-analyses in  
    Thomas, Sweeney, and Somayaji (2014) &lt;doi:10.1080/19466315.2014.924876&gt; and
    Thomas and Roy (2016) &lt;doi:10.1080/19466315.2016.1256229&gt; 
    Wu, Banerjee, Jin, Menon, Martin, and Heatherington(2017) &lt;doi:10.1177/0962280216684528&gt; 
    are included 
    in the package.  The prior distributions for the Bayesian analyses default to
    the posterior predictive distributions derived from these references.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.5.0), rstan (&gt;= 2.17.3), shiny</dc:relation>
  <dc:relation>Imports: foreach,graphics,DoseFinding,stats,mvtnorm,utils,
parallel,doParallel, ggplot2, tidyr, purrr, tibble, dplyr,
glue, waiter</dc:relation>
  <dc:creator>Neal Thomas &lt;snthomas99@gmail.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Neal Thomas [aut, cre] (ORCID: &lt;https://orcid.org/0000-0002-1915-8487&gt;),
  Jing Wu [aut],
  Mike K. Smith [aut]</dc:contributor>
  <dc:rights>GPL (&gt;= 2)</dc:rights>
  <dc:date>2025-10-02</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=clinDR</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.clinDR</dc:identifier>
</oai_dc:dc>
