An R Implementation of the 'Align-GVGD' Method R package agvgd version 0.1.2 CRAN Task View: Omics (https://CRAN.R-project.org/view=Omics) 'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments <doi:10.1136/jmg.2005.033878>. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on <http://agvgd.hci.utah.edu/>. Software Depends: R (>= 2.10) Imports: crayon, dplyr, glue, grantham, magrittr, purrr, rlang, seqinr, stringr, tibble, tidyr, vctrs Suggests: rmarkdown, covr, testthat (>= 3.0.0), Ramiro Magno <ramiro.magno@gmail.com> Comprehensive R Archive Network (CRAN) Ramiro Magno [aut, cre] (ORCID: <https://orcid.org/0000-0001-5226-3441>), Isabel Duarte [aut] (ORCID: <https://orcid.org/0000-0003-0060-2936>), Ana-Teresa Maia [aut] (ORCID: <https://orcid.org/0000-0002-0454-9207>), CINTESIS [cph, fnd] MIT + file LICENSE (https://CRAN.R-project.org/package=agvgd/LICENSE) 2022-09-10 application/tgz https://CRAN.R-project.org/package=agvgd doi:10.32614/CRAN.package.agvgd