(Pre-)Clinical NCA in a Dynamic Shiny App R package aNCA version 0.1.0 An interactive 'shiny' application for performing non-compartmental analysis (NCA) on pre-clinical and clinical pharmacokinetic data. The package builds on 'PKNCA' for core estimators and provides interactive visualizations, CDISC outputs ('ADNCA', 'PP', 'ADPP') and configurable TLGs (tables, listings, and graphs). Typical use cases include exploratory analysis, validation, reporting or teaching/demonstration of NCA methods. Methods and core estimators are described in Denney, Duvvuri, and Buckeridge (2015) "Simple, Automatic Noncompartmental Analysis: The PKNCA R Package" <doi:10.1007/s10928-015-9432-2>. Software Depends: R (>= 4.1) Imports: dplyr, formatters, flextable, ggplot2, magrittr, methods, officer, PKNCA (>= 0.12.1), plotly, purrr, rlang, rlistings, scales, stats, stringr, tern, tidyr, units, utils Suggests: arrow, covr, DT, ggh4x, glue, haven, htmltools, htmlwidgets, jsonlite, knitr, lintr (>= 3.1.2), logger, markdown, mockery, nestcolor, openxlsx2, pak, reactable, reactable.extras, rmarkdown, sass, shiny, shinycssloaders, shinyjs, shinyjqui, shinytest2, shinyWidgets, stringi, testthat (>= 3.0.0), tools, quarto, vdiffr, withr, yaml Valentin Legras <anca.pharmaverse@gmail.com> Comprehensive R Archive Network (CRAN) Ercan Suekuer [aut] (ORCID: <https://orcid.org/0009-0001-1626-1526>), Gerardo Jose Rodriguez [aut] (ORCID: <https://orcid.org/0000-0003-1413-0060>), Pascal Baertschi [aut] (ORCID: <https://orcid.org/0000-0002-6533-0399>), Jana Spinner [aut] (ORCID: <https://orcid.org/0009-0009-2197-9530>), Mateusz Kolomanski [aut] (ORCID: <https://orcid.org/0000-0001-7424-3919>), Lucy Aspridis [aut] (ORCID: <https://orcid.org/0009-0003-1300-3622>), Valentin Legras [aut, cre], F. Hoffmann-La Roche AG [cph, fnd] Apache License (>= 2) 2025-12-09 application/tgz https://CRAN.R-project.org/package=aNCA doi:10.32614/CRAN.package.aNCA en-US