<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Weibull Shape Parameter Tests for Signal Detection</dc:title>
  <dc:title>R package WSPsignal version 1.0.0</dc:title>
  <dc:description>Implementation of Bayesian and frequentist Weibull Shape Parameter (WSP) tests for signal detection in pharmacovigilance based on right-censored time-to-event data to flag associations between drugs and adverse events. The WSP test is based on the assumption of constant hazard reflected by a Weibull type distribution with shape parameters equal to one. Based on the shape parameter estimates (posterior distribution or point estimate), the WSP test method performs a hypothesis test on each shape parameter and combines them to a decision on the presence of a signal. Methods described in Sauzet and Cornelius (2022) &lt;doi:10.3389/fphar.2022.889088&gt;, Sauzet et al. (2024) &lt;doi:10.1007/s40264-024-01460-2&gt;, and Dyck and Sauzet (2025) &lt;doi:10.48550/arXiv.2412.05463&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.5.0)</dc:relation>
  <dc:relation>Imports: methods, Rcpp (&gt;= 0.12.0), RcppParallel (&gt;= 5.0.1), rstan (&gt;=
2.18.1), rstantools (&gt;= 2.4.0), Rdpack, HDInterval, ROCR,
stats, graphics, magrittr, dplyr, tidyr, ggplot2, survival,
furrr</dc:relation>
  <dc:relation>LinkingTo: BH (&gt;= 1.66.0), Rcpp (&gt;= 0.12.0), RcppEigen (&gt;= 0.3.3.3.0),
RcppParallel (&gt;= 5.0.1), rstan (&gt;= 2.18.1), StanHeaders (&gt;=
2.18.0)</dc:relation>
  <dc:creator>Julia Dyck &lt;j.dyck@uni-bielefeld.de&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Julia Dyck [cre],
  Julia Dyck [aut],
  Odile Sauzet [aut]</dc:contributor>
  <dc:rights>MIT + file LICENSE (https://CRAN.R-project.org/package=WSPsignal/LICENSE)</dc:rights>
  <dc:date>2026-07-09</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=WSPsignal</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.WSPsignal</dc:identifier>
</oai_dc:dc>
