Causal Analysis of Observational Time-to-Event Data R package TrialEmulation version 0.0.4.11 Implements target trial emulation methods to apply randomized clinical trial design and analysis in an observational setting. Using marginal structural models, it can estimate intention-to-treat and per-protocol effects in emulated trials using electronic health records. A description and application of the method can be found in Danaei et al (2013) <doi:10.1177/0962280211403603>. Software Depends: R (>= 4.1.0) Imports: broom (>= 0.7.10), checkmate, data.table (>= 1.9.8), DBI, duckdb, formula.tools, lifecycle, lmtest, methods, mvtnorm, Rcpp, sandwich LinkingTo: Rcpp Suggests: knitr, parsnip, rmarkdown, rpart, testthat (>= 3.0.0), withr Isaac Gravestock <isaac.gravestock@roche.com> Comprehensive R Archive Network (CRAN) Isaac Gravestock [aut, cre] (ORCID: <https://orcid.org/0000-0003-0283-2065>), Li Su [aut], Roonak Rezvani [aut] (ORCID: <https://orcid.org/0000-0001-5580-5058>, Original package author), Julia Moesch [aut], Medical Research Council (MRC) [fnd], F. Hoffmann-La Roche AG [cph, fnd] Apache License (>= 2) 2026-04-10 application/tgz https://CRAN.R-project.org/package=TrialEmulation doi:10.32614/CRAN.package.TrialEmulation en-GB