<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Group Sequential Testing of a Treatment Effect Using a Surrogate
Marker</dc:title>
  <dc:title>R package SurrogateSeq version 1.1</dc:title>
  <dc:subject>CRAN Task View: ClinicalTrials (https://CRAN.R-project.org/view=ClinicalTrials)</dc:subject>
  <dc:description>Provides functions to implement group sequential procedures that allow for early stopping to declare efficacy using a surrogate marker and the possibility of futility stopping.   More details are available in: Parast, L. and Bartroff, J (2024) &lt;doi:10.1093/biomtc/ujae108&gt;. A tutorial for this package can be found at &lt;https://www.laylaparast.com/surrogateseq&gt;. A Shiny App implementing the methods can be found at &lt;https://parastlab.shinyapps.io/SurrogateSeqApp/&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.5.0)</dc:relation>
  <dc:relation>Imports: stats, MASS, ggplot2</dc:relation>
  <dc:creator>Layla Parast &lt;parast@austin.utexas.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Layla Parast [aut, cre],
  Jay Bartroff [aut]</dc:contributor>
  <dc:rights>GPL</dc:rights>
  <dc:date>2026-01-08</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=SurrogateSeq</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.SurrogateSeq</dc:identifier>
</oai_dc:dc>
