Analysis of Single-Cell Chromatin Data R package Signac version 1.17.1 CRAN Task View: Omics (https://CRAN.R-project.org/view=Omics) A framework for the analysis and exploration of single-cell chromatin data. The 'Signac' package contains functions for quantifying single-cell chromatin data, computing per-cell quality control metrics, dimension reduction and normalization, visualization, and DNA sequence motif analysis. Reference: Stuart et al. (2021) <doi:10.1038/s41592-021-01282-5>. Software Depends: R (>= 4.1.0), methods Imports: GenomeInfoDb (>= 1.29.3), GenomicRanges, IRanges, Matrix, Rsamtools, S4Vectors, SeuratObject (>= 5.0.2), data.table, dplyr (>= 1.0.0), future, future.apply, ggplot2, rlang, pbapply, tidyr, patchwork, stats, utils, BiocGenerics, stringi, fastmatch, RcppRoll, scales, Rcpp, grid, tidyselect, vctrs, lifecycle, sparseMatrixStats, RSpectra LinkingTo: Rcpp Suggests: Seurat (>= 5.0.2), ggforce, ggrepel, ggseqlogo, testthat (>= 2.1.0), SummarizedExperiment, TFBSTools, motifmatchr, BSgenome, shiny, miniUI, rtracklayer, biovizBase, Biostrings, lsa, MASS, wrswoR, fgsea Tim Stuart <stuartt@a-star.edu.sg> Comprehensive R Archive Network (CRAN) Tim Stuart [aut, cre] (ORCID: <https://orcid.org/0000-0002-3044-0897>), Avi Srivastava [aut] (ORCID: <https://orcid.org/0000-0001-9798-2079>), Paul Hoffman [ctb] (ORCID: <https://orcid.org/0000-0002-7693-8957>), Rahul Satija [ctb] (ORCID: <https://orcid.org/0000-0001-9448-8833>) MIT + file LICENSE (https://CRAN.R-project.org/package=Signac/LICENSE) 2026-04-06 application/tgz https://CRAN.R-project.org/package=Signac doi:10.32614/CRAN.package.Signac