<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Detection of Kataegis</dc:title>
  <dc:title>R package SeqKat version 0.0.9</dc:title>
  <dc:description>Kataegis is a localized hypermutation occurring when a region is enriched in somatic SNVs. Kataegis can result from multiple cytosine deaminations catalyzed by the AID/APOBEC family of proteins. This package contains functions to detect kataegis from SNVs in BED format. This package reports two scores per kataegic event, a hypermutation score and an APOBEC mediated kataegic score. Yousif, F. et al.; The Origins and Consequences of Localized and Global Somatic Hypermutation; Biorxiv 2018 &lt;doi:10.1101/287839&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 2.15.1), foreach, doParallel</dc:relation>
  <dc:relation>Imports: Rcpp (&gt;= 0.11.0)</dc:relation>
  <dc:relation>LinkingTo: Rcpp</dc:relation>
  <dc:relation>Suggests: testthat, doMC, rmarkdown, knitr</dc:relation>
  <dc:creator>Paul C. Boutros &lt;pboutros@sbpdiscovery.org&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Fouad Yousif [aut],
  Xihui Lin [aut],
  Fan Fan [aut],
  Christopher Lalansingh [aut],
  John Macdonald [aut],
  Paul C. Boutros [cre]</dc:contributor>
  <dc:rights>GPL (&gt;= 2)</dc:rights>
  <dc:date>2026-01-24</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=SeqKat</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.SeqKat</dc:identifier>
</oai_dc:dc>
