<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Receptor Abundance Estimation using Feature Selection and Gene
Set Scoring</dc:title>
  <dc:title>R package STREAK version 1.0.0</dc:title>
  <dc:description>Performs receptor abundance estimation for single cell RNA-sequencing data using a supervised feature selection mechanism and a thresholded gene set scoring procedure. Seurat's normalization method is described in: Hao et al., (2021) &lt;doi:10.1016/j.cell.2021.04.048&gt;, Stuart et al., (2019) &lt;doi:10.1016/j.cell.2019.05.031&gt;, Butler et al., (2018) &lt;doi:10.1038/nbt.4096&gt; and Satija et al., (2015) &lt;doi:10.1038/nbt.3192&gt;. Method for reduced rank reconstruction and rank-k selection is detailed in: Javaid et al., (2022) &lt;doi:10.1101/2022.10.08.511197&gt;. Gene set scoring procedure is described in: Frost et al., (2020) &lt;doi:10.1093/nar/gkaa582&gt;. Clustering method is outlined in: Song et al., (2020) &lt;doi:10.1093/bioinformatics/btaa613&gt; and Wang et al., (2011) &lt;doi:10.32614/RJ-2011-015&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 2.10)</dc:relation>
  <dc:relation>Imports: Ckmeans.1d.dp, Matrix, Seurat, SPECK, stats, VAM</dc:relation>
  <dc:relation>Suggests: knitr, rmarkdown</dc:relation>
  <dc:creator>Azka Javaid &lt;azka.javaid.gr@dartmouth.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>H. Robert Frost [aut],
  Azka Javaid [aut, cre]</dc:contributor>
  <dc:rights>GPL (&gt;= 2)</dc:rights>
  <dc:date>2023-11-17</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=STREAK</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.STREAK</dc:identifier>
</oai_dc:dc>
