Survival Mediation Analysis of High-Dimensional Proteogenomic Data R package SMAHP version 0.0.5 SMAHP (pronounced as SOO-MAP) is a novel multi-omics framework for causal mediation analysis of high-dimensional proteogenomic data with survival outcomes. The full methodological details can be found in our recent preprint by Ahn S et al. (2025) <doi:10.48550/arXiv.2503.08606>. Software Depends: R (>= 3.5.0) Imports: data.table, fdrtool, ncvreg, penAFT, survival, stats, glmnet Suggests: knitr, rmarkdown, testthat (>= 3.0.0) Weijia Fu <weijia.fu@mountsinai.org> Comprehensive R Archive Network (CRAN) Seungjun Ahn [aut] (ORCID: <https://orcid.org/0000-0002-4816-8924>), Weijia Fu [cre, aut] (ORCID: <https://orcid.org/0009-0002-5955-3534>), Zhigang Li [ctb] GPL-3 2025-03-24 application/tgz https://CRAN.R-project.org/package=SMAHP doi:10.32614/CRAN.package.SMAHP en-US