Single Cell Oriented Reconstruction of PANDA Individually Optimized Networks R package SCORPION version 1.3.2 Constructs cell-type–specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into super-cells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor–target regulatory relationships. It also provides statistical methods for differential edge analysis. Software Depends: R (>= 3.5.0) Imports: cli, methods, irlba, igraph, RANN, Matrix, pbapply, dplyr, furrr, future Suggests: RhpcBLASctl, testthat Daniel Osorio <daniecos@uio.no> Comprehensive R Archive Network (CRAN) Daniel Osorio [aut, cre] (ORCID: <https://orcid.org/0000-0003-4424-8422>), Marieke L. Kuijjer [aut] (ORCID: <https://orcid.org/0000-0001-6280-3130>) GPL-3 2026-03-10 application/tgz https://CRAN.R-project.org/package=SCORPION doi:10.32614/CRAN.package.SCORPION