<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Rare Variant Analysis and Genetic Simulations</dc:title>
  <dc:title>R package Ravages version 1.2.0</dc:title>
  <dc:description>Rare variant association tests: burden tests (Bocher et al. 2019 &lt;doi:10.1002/gepi.22210&gt;) and the Sequence Kernel Association Test (Bocher et al. 2021 &lt;doi:10.1038/s41431-020-00792-8&gt;) in the whole genome using the RAVA-FIRST approach (Bocher et al. 2022 &lt;doi:10.1371/journal.pgen.1009923&gt;). Ravages also enables to perform genetic simulations (Bocher et al. 2023 &lt;doi:10.1002/gepi.22529&gt;).</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.5.0), Rcpp, RcppParallel, methods, gaston, mlogit (&gt;=
1.1-0)</dc:relation>
  <dc:relation>Imports: Formula, dfidx, parallel, bedr, curl, data.table</dc:relation>
  <dc:relation>LinkingTo: Rcpp, RcppParallel, RcppEigen, gaston, BH</dc:relation>
  <dc:relation>Suggests: knitr, rmarkdown</dc:relation>
  <dc:creator>Ozvan Bocher &lt;ozvan.bocher@univ-brest.fr&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Ozvan Bocher [aut, cre],
  Hervé Perdry [aut],
  Gaelle Marenne [aut]</dc:contributor>
  <dc:rights>GPL-3</dc:rights>
  <dc:date>2026-02-27</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=Ravages</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.Ravages</dc:identifier>
</oai_dc:dc>
