Dose-Finding Methods for Non-Binary Outcomes

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Documentation for package ‘UnifiedDoseFinding’ version 0.1.10

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get_oc_gBOIN_continuous Generate operating characteristics for finding the maximum tolerated dose (MTD) using gBOIN design
get_oc_gBOIN_TB Generate operating characteristics for finding the maximum tolerated dose (MTD) defined by Toxicity Burden (TB) Score using gBOIN design
get_oc_Ivanova_binary Generate operating characteristics for finding the maximum tolerated dose (MTD) of binary endpoint using design by Ivanova et al (2009)
get_oc_Ivanova_continuous Generate operating characteristics for finding the maximum tolerated dose (MTD) of continuous endpoint using design by Ivanova et al (2009)
get_oc_QuasiBOIN Generate operating characteristics for finding the maximum tolerated dose (MTD) defined by Equivalent Score (ET) using Quasi-CRM design using gBOIN
get_oc_RQ_CRM Generate operating characteristics for finding the maximum tolerated dose (MTD) defined by Equivalent Score (ET) using Quasi-CRM design
next_gBOIN_continuous Determine the dose for the next cohort of new patients for single-agent trials that aim to find a maximum tolerated dose (MTD) using gBOIN design
next_gBOIN_TB Determine the dose for the next cohort of new patients for single-agent trials that aim to find a maximum tolerated dose (MTD) defined by Toxicity Burden (TB) Score using gBOIN design
next_Ivanova_binary Determine the dose for the next cohort of new patients of binary endpoint using design by Ivanova et al (2009)
next_Ivanova_continuous Determine the dose for the next cohort of new patients using Inanova design
next_QuasiBOIN Determine the dose for the next cohort of new patients based on equivalent score (ET)-defined target using gBOIN design
next_RQ_CRM Determine the dose for the next cohort of new patients using Quasi-CRM design
select_mtd_gBOIN_continuous Select the maximum tolerated dose (MTD) for single agent trials using gBOIN design
select_mtd_gBOIN_TB Select the maximum tolerated dose (MTD) defined by Toxicity Burden (TB) Score for single agent trials using gBOIN design
select_mtd_Ivanova_binary Select the maximum tolerated dose (MTD) of binary endpoint for single agent trials using design by Ivanova et al (2009)
select_mtd_Ivanova_continuous Select the maximum tolerated dose (MTD) for single agent trials of continuous endpoint using design by Ivanova et al (2009)
select_mtd_QuasiBOIN Select the maximum tolerated dose (MTD)-defined by equivalent score (ET) using gBOIN design
select_mtd_RQ_CRM Select the maximum tolerated dose (MTD) using Quasi-CRM design