Designing Multi-Arm Multi-Stage Studies

Documentation for package ‘MAMS’ version 3.0.1

.onAttach	.onAttach
mams	Function to design multi-arm multi-stage studies with normal endpoints
mams.sim	Simulating multi-arm multi-stage designs
MAMSNews	Shows changes and news
new.bounds	Function to update boundaries based on observed sample sizes
ordinal.mams	Function to design multi-arm multi-stage studies with ordinal or binary endpoints
plot.MAMS	Plot method for MAMS objects
plot.MAMS.stepdown	Plot method for MAMS.stepdown objects
print.MAMS	Generic print function for class MAMS.
print.MAMS.stepdown	Generic print function for class MAMS.stepdown.
stepdown.mams	Function to find stopping boundaries for a 2- or 3-stage (step-down) multiple-comparisons-with-control test.
stepdown.update	Update the stopping boundaries of multi-arm multi-stage study at an interim analysis, allowing for unplanned treatment selection and/or sample-size reassessment.
summary.MAMS	Generic summary function for class MAMS.
summary.MAMS.stepdown	Generic summary function for class MAMS.stepdown.
tite.mams	Function to design multi-arm multi-stage studies with time-to-event endpoints