Nonlinear Mixed Effects Models in Population PK/PD, Data

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Documentation for package ‘nlmixr2data’ version 2.0.9

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Bolus_1CPT 1 Compartment Model Simulated Data from ACOP 2016
Bolus_1CPTMM 1 Compartment Model w/ Michaelis-Menten Elimination
Bolus_2CPT 2 Compartment Model
Bolus_2CPTMM 2 Compartment Model with Michaelis-Menten Clearance
Infusion_1CPT 1 Compartment Model Simulated Data from ACOP 2016
Infusion_1CPTMM 1 Compartment Model w/MM elimination Simulated Data from ACOP 2016
Infusion_2CPT 2 Compartment Model with Infusion Simulated Data from ACOP 2016
Infusion_2CPTMM 2 Compartment Model w/MM elimination Simulated Data from ACOP 2016
invgaussian Inverse Guassian absorption model
mavoglurant Mavoglurant PK data
metabolite Parent/Metabolite dataset
nimoData Nimotuzumab PK data
nmtest One compartment test dataset showing NONMEM 7.4.3 output
Oral_1CPT 1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
Oral_1CPTMM 1 Compartment Model w/ Oral Absorption & Michaelis-Menten Elimination
Oral_2CPT 2 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
Oral_2CPTMM 1 Compartment Model w/ Oral Absorption & Michaelis-Menten Elimination
pheno_sd Single Dose Phenobarbitol PK/PD
pump Pump failure example dataset
rats Pregnant Rat Diet Experiment
theo_md Multiple dose theophylline PK data
theo_sd Multiple dose theophylline PK data
Wang2007 Simulated Data Set for comparing objective functions
warfarin Warfarin PK/PD data
wbcSim Simulated Friberg Myelosuppression model (Yuan Xiong)